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Dark Circles Under Eye: Polynucleotide Treatment Available Near You!

Updated: Apr 26


The desire for skin that looks young and healthy has led to many new beauty products. Among these, polynucleotides have shown a lot of promise, especially when it comes to treating sensitive skin under the eyes. We look into the science behind polynucleotides and how they might help rejuvenate the area under your eyes in this blog post.

Understanding Polynucleotides:

Polynucleotides are chains of nucleotides, the building blocks of nucleic acids like DNA and RNA. In skincare formulations, polynucleotides derived from salmon DNA or yeast serve as bioactive compounds with remarkable properties. These compounds are revered for their ability to stimulate cellular regeneration and promote tissue repair.

polynucleotide under eyes before and after
Polynucleotide under eyes before and after

Dark Circles Under Eyes:

The skin under the eyes is notoriously thin and delicate, making it prone to various signs of aging such as fine lines, wrinkles, and dark circles. Factors like sun exposure, stress, and genetics can exacerbate these concerns, leading many individuals to seek effective solutions to combat under-eye aging.

The Role of Polynucleotides Under Eyes:

Polynucleotides offer a multifaceted approach to under-eye rejuvenation. Firstly, they possess potent antioxidant properties, which help neutralize free radicals and mitigate oxidative stress—a major contributor to premature aging. By shielding delicate under-eye skin from environmental aggressors, polynucleotides aid in preserving its youthful appearance.

Furthermore, polynucleotides have been shown to enhance collagen and elastin synthesis. Collagen and elastin are essential proteins that provide structural support and elasticity to the skin. As we age, their production diminishes, leading to sagging and loss of firmness. By promoting collagen and elastin production, polynucleotides help restore resilience and suppleness to the under-eye area, reducing the appearance of wrinkles and fine lines.

Moreover, polynucleotides possess remarkable hydrating properties. They bolster the skin's natural moisture barrier, preventing transepidermal water loss and maintaining optimal hydration levels. Proper hydration is crucial for ensuring the skin under the eyes appears plump, smooth, and luminous, diminishing the appearance of tiredness and fatigue.

Clinical Evidence:

Numerous studies have highlighted the efficacy of polynucleotides in aesthetic medicine. Clinical trials have demonstrated improvements in skin texture, elasticity, and hydration following the use of polynucleotides-based formulations.(1) Moreover, patients report a reduction in the visibility of dark circles and puffiness, resulting in a more refreshed and youthful eye contour. (2)

Polynucleotide before and after
Polynucleotide before and after

The individual satisfaction score following polynucleotide treatment averaged 8 out of a maximum possible score of 10. Based on independent evaluations of photographs and an overall assessment of skin texture, roughness, elasticity, and brightness, there was a comprehensive improvement in overall skin quality and texture from baseline to follow-up, with an average improvement of +10%. (3)

In the quest for age-defying aesthetic solutions, polynucleotide injection have emerged as a formidable ally, particularly in addressing the unique concerns of the under-eye area. With their potent antioxidant, collagen-boosting, and hydrating properties, polynucleotides offer a holistic approach to under-eye rejuvenation, helping you achieve a more youthful and radiant gaze. Consider incorporating polynucleotides into your aesthetic treatment plan and unlock the transformative power of this innovative ingredient.

Polynucleotides are believed to have effects in addition to just adding volume, while HA fillers are mostly used to add volume to certain areas. Some of these effects could be on the texture, elasticity, and general renewal of the skin.

When eyes mesotherapy are used together in a treatment, the super benefits start to show. Polynucleotide's ability to fight free radicals makes hyaluronic acid work longer, which slows its breakdown by about 40%.

Go to Eyes Mesotherapy to learn more.

1. Raposio E, Guida C, Coradeghini R, et al. In vitro polydeoxyribonucleotide effects on human pre‐adipocytes. Cell Prolif. 2008;41(5):739‐754 [PMC free article]

2. Cavallini M, Bartoletti E, Maioli L, et al. Consensus report on the use of PN‐HPT (polynucleotides highly purified technology) in aesthetic medicine. J Cosmet Dermatol. 2021;20(3):922‐928. [PMC free article]

3. Matera G, Dodici N, Raichi M. Improving on laser: biorevitalization of stretch marks, the polynucleotides infiltrations combined with CO2 laser option. Aesth Med. 2020;6(2):17‐24

Check with Skinoza team to see how well you are handling the polynucleotide treatment so you understand what can be done with it. This is all about helping you stay safe and at less of a risk of serious problems when using these.

Ask your trusted Skinoza clinic today for the procedure that suits you! Find Polynucleotide Treatment Near You:

1. Skinoza Orpington, Bromley near Chislehurst, Bickley, Beckenham, West Wickham, Sidcup and Swanley

2. Skinoza Greenwich near Canary Warf, Deptford, Surrey Quays and Kidbrooke Village

3. Skinoza Blackhorse Road, Walthamstow near Tottenham Hale and Seven Sisters

We are experts in polynucleotide treatment in London

Please feel free to get in touch for a free consultation and start your journey towards enhanced beauty.


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