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Polynucleotides vs. Profhilo: Which Treatment Is Right for You?

In the world of aesthetic treatments, Polynucleotide and Profhilo injections have become popular options for skin rejuvenation, hydration, and anti-aging. Both treatments aim to revitalise the skin, improve texture, and restore a youthful glow, but they work through different mechanisms and are best suited for distinct skin concerns. In this article, we will explore the differences between Polynucleotides and Profhilo, their benefits, potential side effects, and how to choose the right treatment for your needs.

What Are Polynucleotide Injections?

Polynucleotide injections are a form of regenerative treatment that utilises naturally occurring polynucleotides—components of DNA and RNA—to repair and regenerate tissue. These injections work by stimulating fibroblasts, the cells responsible for producing collagen, to promote skin elasticity, hydration, and overall skin health.

Polynucleotides are especially useful in treating aging skin, fine lines, and skin that has been damaged by environmental factors like sun exposure. They offer a gentle but effective solution for those seeking skin renewal with minimal downtime.

What Is Profhilo?

Profhilo is a hyaluronic acid-based injectable treatment designed to hydrate the skin, improve elasticity, and smooth out fine lines. Unlike traditional dermal fillers that add volume to specific areas, Profhilo works by spreading evenly across the treated area, improving the skin’s overall texture and hydration.

Profhilo contains one of the highest concentrations of hyaluronic acid available on the market and acts as a “bio-remodelling” treatment, stimulating the production of elastin and collagen over time.

Key Differences Between Polynucleotides and Profhilo


Polynucleotides vs. Profhilo
Polynucleotides vs. Profhilo

Though both treatments focus on skin rejuvenation, they work differently, making them ideal for different types of skin concerns.

  1. Mechanism of Action

    • Polynucleotides: Stimulate the body’s natural healing and repair mechanisms, promoting cellular regeneration. They work on the deeper layers of the skin to restore collagen production and improve skin health from the inside out.

    • Profhilo: Hydrates the skin through high concentrations of hyaluronic acid, which draws moisture to the surface layers of the skin. Profhilo spreads evenly to smooth and hydrate the skin, giving it a more youthful appearance.

  2. Target Concerns

    • Polynucleotides: Suitable for treating sun-damaged skin, scars, and fine lines. It is also effective for those looking to repair damaged skin cells and stimulate deeper tissue regeneration.

    • Profhilo: Targets skin hydration and elasticity. It is ideal for people with dehydrated or sagging skin who want a more lifted and youthful appearance without adding volume to specific areas.

  3. Duration of Effects

    • Polynucleotides: The results of polynucleotide injections typically become visible within 2-4 weeks, and the effects can last for up to 9 months. Regular maintenance treatments are often recommended.

    • Profhilo: The benefits of Profhilo generally last for about 6 months after two treatments, spaced one month apart. Maintenance treatments may be needed to prolong results.

Side Effects: Polynucleotides vs. Profhilo

As with any injectable treatment, there are potential side effects to both Polynucleotides and Profhilo. However, both treatments are considered safe and non-invasive, with minimal downtime.

Polynucleotides Side Effects

  • Redness and Swelling: Common around the injection sites but usually subsides within a few hours to a day.

  • Bruising: Mild bruising may occur, particularly in sensitive areas like the face, but it typically resolves within a few days.

  • Lumps: Small lumps or nodules can form at the injection site but generally disappear on their own.

To manage these side effects, it is recommended to avoid direct sunlight, excessive heat, and strenuous exercise for 24-48 hours after the treatment. Gentle cooling of the area and following the aftercare advice of your practitioner can also help to minimise discomfort.

Profhilo Side Effects

  • Redness and Swelling: This is a common side effect but usually goes away within a day or two.

  • Bruising: Similar to Polynucleotides, bruising can occur around the injection sites.

  • Tenderness: Some patients report slight tenderness or discomfort around the areas where the Profhilo was injected.

The aftercare for Profhilo is quite simple and similar to that of Polynucleotides. Avoiding heavy exercise, alcohol, and exposure to high temperatures is recommended for the first 24-48 hours post-treatment.

For further reading on the safety and effectiveness of polynucleotide and Profhilo treatments, you can explore these studies on Polynucleotides for Skin Rejuvenation and Profhilo's Impact on Skin Elasticity.

How to Choose Between Polynucleotide and Profhilo Treatments

Choosing between Polynucleotides and Profhilo depends largely on your specific skin concerns and goals.

  • For Deeper Skin Repair and Anti-Aging: Polynucleotides may be a better choice if you are seeking to improve skin damage at a deeper level, including sun damage, acne scars, and fine lines. Polynucleotides excel in stimulating collagen production and cellular repair, making them ideal for aging or damaged skin.

  • For Hydration and a Youthful Glow: If your primary concern is skin hydration and you want an overall improvement in skin texture without the need for added volume, Profhilo might be the better option. Profhilo is particularly effective for those with dull or sagging skin who want a radiant, smoother complexion.

Cost of Polynucleotide and Profhilo Treatments in London

The cost of both treatments can vary depending on the clinic and practitioner. In London, the average price for polynucleotide injections ranges from £200 to £400 per session, while Profhilo treatments generally cost between £250 and £500 for the initial course of two treatments. Skinoza Clinic in Orpington, Bromley, and Kent offers both polynucleotide and Profhilo treatments at competitive prices, with flexible options for maintenance sessions.

Conclusion

Both Polynucleotide and Profhilo injections offer unique benefits in the world of aesthetic treatments. Whether you need deeper skin repair through polynucleotides or enhanced hydration and elasticity with Profhilo, both treatments have proven effective in improving skin quality. Read more about polinucleotides here


Check with Skinoza team to see how well you are handling the polynucleotide treatment so you understand what can be done with it. This is all about helping you stay safe and at less of a risk of serious problems when using these.


Ask your trusted Skinoza clinic today for the procedure that suits you! Find Profhilo Near You and Polynucleotide Treatment Near You:

1. Skinoza Orpington, Bromley near Chislehurst, Bickley, Beckenham, West Wickham, Sidcup and Swanley

2. Skinoza Greenwich near Canary Warf, Deptford, Surrey Quays and Kidbrooke Village

3. Skinoza Blackhorse Road, Walthamstow near Tottenham Hale and Seven Sisters


We are experts in polynucleotide injections  and Profhilo injections in London


Please feel free to get in touch for a free consultation and start your journey towards enhanced beauty.





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